CD4 T cells activate CD8 T cells through an indirect process involving an antigen presenting cell (APC), normally a conventional dendritic cell (DC). An APC presents a peptide to a naive CD4 T cell via a Class II MHC molecule. The CD4 T cell becomes active and differentiates into a T helper 1 (Th1) cell … Continue reading How do CD4 T cells activate CD8 T cells?
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